Genome Architecture and Function agenda

Learning genomic energy landscapes from experiments

Michele Di Pierro - Northeastern University, Boston, USA

A Physicochemical Basis for Chromosome Organization and Structural Heterogeneity Across Human Cell Types

Ryan Cheng - University of Kentucky, USA

Machine learning techniques for analyzing fluorescent microscopy images

Rumen Stamatov - IMB, Sofia, Bulgaria

An introduction to LAMMPS (Large-scale Atomic/Molecular Massively Parallel Simulator) for Biomolecular applications (part 1)

Bradley Keister - University of California San Diego, USA

An introduction to LAMMPS (Large-scale Atomic/Molecular Massively Parallel Simulator) for Biomolecular applications (part 2)

Bradley Keister - University of California San Diego, USA

Imaging chromosome structure, dynamics and mechanics

Antoine Coulon - Institut Curie, France

Dynamics and precision of transcription during development

Nathalie Dostatni - Institut Curie, France

Introduction to DNA Supercoiling and its effects on transcription

Herbert Levine - Northeastern University, Boston, USA

Principles in analyzing bulk, single-cell and spatial sequencing experiments

Sébastien Lemaire - Institut Curie, Paris, France

What we see in Hi-C

Aleksandra Galitsyna - Massachusetts Institute of Technology, USA

What we see in Hi-C

Aleksandra Galitsyna - Massachusetts Institute of Technology, USA

Modeling the Genome: A View by a Physicist

Jose Onuchic - Rice University, Houston, USA

Talk: 40 min., QA: 20 min.

Learning from bacterial genomes placed in a eukaryotic nucleus.

Romain Koszul - Institute Pasteur, Paris, France

Talk: 20 min., QA: 10 min.

Multiscale modeling of chromosomal DNA and the physical processes underlying epigenetic regulation

Andrew Spakowitz - Stanford University, USA

Talk: 20 min., QA: 10 min.

Liquid crystal chromosome organization in sperm

Guillermo Orsi - IAB, Grenoble, France

Talk: 20 min., QA: 10 min.

SMC protein complexes are efficient DNA loop extruders: what can stop them?

Cees Dekker - TU, Delft, The Netherlands

Talk: 40 min., QA: 20 min.

3d genome folding

Erez Lieberman Aiden - Baylor College of Medicine, USA

Talk: 20 min., QA: 10 min.

Chromosomes as memory machines

Leonid Mirny - Massachusetts Institute of Technology, USA

Talk: 20 min., QA: 10 min.

Targeting DNA repair defects for cancer therapy: challenges and new opportunities

Haico van Attikum - Leiden University Medical Center, The Netherlands

Talk: 40 min., QA: 20 min.

Dynamic of DNA Repair during Cell Cycle Progression

Stoyno Stoynov - IMB, Sofia, Bulgaria

Talk: 20 min., QA: 10 min.

A new role for SMC protein complexes in the maintenance of replication fork stability

Philippe Pasero - IGH, Montpellier, France

Talk: 20 min., QA: 10 min.

Spatial regulation of yeast telomere clustering by aggregation and wetting

Vittore Scolari - Institut Curie, France

Talk: 20 min., QA: 10 min.

Theory of loop extrusion by condensin by the scrunching mechanism

Dave Thirumalai - The University of Texas at Austin, USA

Talk: 20 min., QA: 10 min.

On the spatial positioning and compartmental polarization of human chromosomes

Ryan Cheng - University of Kentucky, USA

Talk: 20 min., QA: 10 min.

Shedding light on homology search in living cells

Angela Taddei - Institut Curie, Paris, France

Talk: 20 min., QA: 10 min.

Towards Understanding the Transcription Code

Peter Wolynes - Rice University, Houston, USA

Talk: 20 min., QA: 10 min.

Regulatory architecture of cell identity and housekeeping genes

Alessandra Dall'Agnese - Massachusetts Institute of Technology, USA

Talk: 20 min., QA: 10 min.

PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends

Simon Alberti - The Biotechnology Center (BIOTEC) TU, Dresden, Germany

Talk: 20 min., QA: 10 min.

Histone variant H2A.Z and chromatin: an epigenetic crosstalk

Stefan Dimitrov - Université Grenoble Alpes, France

Talk: 40 min., QA: 20 min.

Transcription (Nuclear transcriptional bodies)

Nadine L. Vastenhouw - University de Lausanne, Switzerland

Talk: 20 min., QA: 10 min.

Imaging of transcription dynamics and genome organization

Tineke Lenstra - NKI, Amsterdam, The Netherlands

Talk: 20 min., QA: 10 min.

Supercoling and transcription

Herbert Levine - Northeastern University, Boston, USA

Talk: 20 min., QA: 10 min.

Wiring of Animal Gene Regulatory Networks is Enabled by the Evolution of 3D Folding Mechanisms

Heather Marlow - University of Chicago, USA

Talk: 20 min., QA: 10 min.

INO80 Chromatin Regulators in avoiding Transcription-Induced Replication Stress

Anastas Gospodinov - IMB, Sofia, Bulgaria

Talk: 20 min., QA: 10 min.

PARPi-induced alterations in PARP1 dynamics in living cells

Radoslav Aleksandrov - IMB, Sofia, Bulgaria

Talk: 20 min., QA: 10 min.

Role of histone deacetylation at replication fork stalls

Andres Aguilera - CABIMER, Sevilla, Spain

Talk: 20 min., QA: 10 min.

Mechanistic Studies of HDAC Inhibitors Alone and In Combination with eIF4A Inhibition

Susan Bates - Columbia University, USA

Talk: 20 min., QA: 10 min.

Landscapes of genomic architecture across evolution

Michele Di Pierro - Northeastern University, Boston, USA

Talk: 20 min., QA: 10 min.

3D Architecture of Mammalian Genomes

Olga Dudchenko - Baylor College of Medicine, USA

Talk: 20 min., QA: 10 min.

DNA replication timing and oncogenic chromosomal translocations

Mihaela Peycheva - Institute of Molecular Pathology, Vienna, Austria

Talk: 20 min., QA: 10 min.

Meeting Conclusion