Abstracts
Active or Passive? Disentangling Mechanisms of Chromatin Compartmentalization
Deepti Kannan
Massachusetts Institute of Technology
June 5, Day 1, 16:00 - 18:00
Amino acid coevolution reveals novel monomer conformations in DNA-binding response regulators
Mayu Shibata
Ochanomizu University
June 7, Day 3, 15:30 - 17:30
Bacterial DNA organization by ParB proteins
Miloš Tišma
Technical University of Delft
June 7, Day 3, 15:30 - 17:30
Budding yeast complete DNA synthesis after chromosome segregation begins
Tsvetomira Ivanova
Medical University Plovdiv, Bulgaria
June 5, Day 1, 16:00 - 18:00
Chromosomes mechanics under perturbation
Colin Morand
Institut Curie
June 7, Day 3, 15:30 - 17:30
Comparing genomes to infer functional interactions among genes
Andrea Falcon
Center for Theoretical Biological Physics - Northeastern University
June 5, Day 1, 16:00 - 18:00
Compartmentalization of an artificial bacterial chromosomes in budding yeast
Léa MENEU
Institut Pasteur
June 7, Day 3, 15:30 - 17:30
Contribution of the Bicoid domains to the dynamics of hunchback expression boundary establishment
Yang YU
Institut Curie, France
June 7, Day 3, 15:30 - 17:30
Deregulated levels of RUVBL1 induce transcription-dependent replication stress
Rositsa Hristova
Institute of Molecular Biology, BAN
June 5, Day 1, 16:00 - 18:00
Differential NudC gene expression affects abiotic stress response in Arabidopsis thaliana
Dimitar Todorov
Institute of Plant Physiology and Genetics - BAS
June 7, Day 3, 15:30 - 17:30
DNA replication timing directly regulates the frequency of oncogenic translocations
Mihaela Peycheva
Institute for Molecular Pathology
June 7, Day 3, 15:30 - 17:30
DNA supercoiling-transcription interplay in the presence of nucleosomes
Shubham Tripathi
Yale University
June 7, Day 3, 15:30 - 17:30
Drugs targeting chromatin/transcription stress for the treatment of Pancreatic Cancer.
Maryam Safari
Columbia University
June 7, Day 3, 15:30 - 17:30
Dynamics of mitotic chromosomes
Rumen Stamatov
Bulgarian Academy of Sciences
June 7, Day 3, 15:30 - 17:30
Elucidating Meiotic Recombination and Crossover Interference using Polymer Physics Modelling
Ariana Tse
Stanford University
June 7, Day 3, 15:30 - 17:30
Epigenetic mechanisms of leg regeneration in the cricket Gryllus Bimaculatus
LOUVIER Maëlle
PhD Student
June 7, Day 3, 15:30 - 17:30
Evolution of Chromosome compartment X in Lepidopterans
Abhratanu Saha
Institut Curie
June 7, Day 3, 15:30 - 17:30
Holocentric Bombyx mori chromosomes segregate into three genome-wide compartments
Emily Navarrete
Massachusetts Institute of Technology
June 7, Day 3, 15:30 - 17:30
Identification of histone residues of relevance in transcription-replication conflicts
Iván Núñez-Martín
CABIMER (University of Seville)
June 7, Day 3, 15:30 - 17:30
Importance of Histone Acetyltransferase 1 as a novel acyl transferase
Iva Ugrinova
Institute of Molecular Biology "Roumen Tsanev" - BAS
June 7, Day 3, 15:30 - 17:30
Insulin receptor condensates in insulin sensitivity and resistance
Alessandra Dall'Agnese
Whitehead Institute
June 5, Day 1, 16:00 - 18:00
Interphase chromosomes of the Aedes aegypti mosquito are liquid crystalline and can sense mechanical cues
Vinicius Contessoto
Rice University
June 5, Day 1, 16:00 - 18:00
Investigating human chromosome organization by whole-genome simulations
Matheus Mello
Rice University
June 7, Day 3, 15:30 - 17:30
Kinetics of SARS-CoV-2 entry into cells
Aleksandar Atemin
Institute of Molecular Biology, Bulgarian Academy of Sciences
June 5, Day 1, 16:00 - 18:00
Learning the rules of gene regulation: from reporters to endogenous expression
Gonçalo Fernandes
Institut Curie
June 5, Day 1, 16:00 - 18:00
Mechanism and kinetics of recruitment and dissociation of RPA protein involved in the repai of DNA protein crosslinks (DPCs)
Sonya Uzunova
Institute of Molecular Biology
June 5, Day 1, 16:00 - 18:00
Mechanisms, regulation and biological functions of TopBP1 condensates
Elia MOARBESS
CNRS
June 7, Day 3, 15:30 - 17:30
Modeling chromosomes using the full-inversion method
Antonio Oliveira Jr
CTBP - Rice University
June 7, Day 3, 15:30 - 17:30
Modulation of the Human Erythroid Plasma Membrane Calcium Pump (PMCA4b) Expression by Polymorphic Genetic Variants
Orsolya Mózner
Research Centre for Natural Sciences, Budapest, Hungary; Semmelweis University, Budapest, Hungary
June 7, Day 3, 15:30 - 17:30
Optimization strategies for the structural ensemble analysis of chromatin compartments versus subcompartments
Ronaldo Oliveira
Rice University - CTBP
June 7, Day 3, 15:30 - 17:30
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
Nagaraja Chappidi
Technische Universität Dresden
June 5, Day 1, 16:00 - 18:00
PARP1 retention by PARP inhibitors delays downstream repair events and drives cytotoxicity
Petar-Bogomil Kanev
Institute of Molecular Biology - Bulgarian Academy of Sciences
June 7, Day 3, 15:30 - 17:30
PHASE SEPARATION OF AB COMPARTMENTS MODULATED BY LAMINA-CHROMATIN INTERACTION
Esteban Dodero-Rojas
Rice University
June 5, Day 1, 16:00 - 18:00
Physics-Based Modeling of Chromatin Organization and Epigenetic Stability
Joseph Wakim
Stanford University, Spakowitz Lab
June 7, Day 3, 15:30 - 17:30
Polymer folding through active processes – implications for genome organization
Andriy Goychuk
Massachusetts Institute of Technology
June 5, Day 1, 16:00 - 18:00
RECONSTITUTING A CENP-A BASED CENTROMERE IN Bombyx mori
Pablo Jesus Leiva
Institut Curie
June 5, Day 1, 16:00 - 18:00
Replication Identifier (Repli-ID) identifies Rox1 and Lge1 as new components of the replication stress response
Sophie van der Horst
LUMC
June 7, Day 3, 15:30 - 17:30
Role of DNA-RNA helicases in genome instability
Mar Bustamante
CABIMER (University of Seville)
June 5, Day 1, 16:00 - 18:00
Role of the nuclear pore protein TPR in chromatin organization
Narat Zoé
IGH (Institut de Génétique Humaine) - CNRS
June 7, Day 3, 15:30 - 17:30
Single-molecule analysis of cytosolic DNA sensor sequestration by chromatin binding
Raquel Merino Urteaga
Johns Hopkins University
June 7, Day 3, 15:30 - 17:30
Spatiotemporal Regulation of Cohesin DSB Response Revealed by Super-Resolution Imaging and vfCRISPR
Franklin Avilés-Vázquez
Johns Hopkins University
June 5, Day 1, 16:00 - 18:00
Specificity in transcription factor clustering is governed by DNA binding, IDRs are interchangeable
Shivali Dongre
University of Lausanne
June 5, Day 1, 16:00 - 18:00
Steps towards a theory of loop extrusion
Henrik Pinholt
MIT
June 7, Day 3, 15:30 - 17:30
Structural and functional study of the Rad51 nucleofilament
Fadma Lakhal
Institut Curie
June 5, Day 1, 16:00 - 18:00
Synteny in mammalian genome evolution
Alexander Moffett
Northeastern University
June 7, Day 3, 15:30 - 17:30
Targeted disruption of transcription bodies causes widespread activation of transcription
Martino Ugolini
UNIL (Lausanne)
June 7, Day 3, 15:30 - 17:30
The double-edged sword of transcription factor clustering
Jos Meeussen
Netherlands Cancer Institute
June 7, Day 3, 15:30 - 17:30
The evolution of three-dimensional genome structure following WGDs in the sea lamprey P. marinus
Sébastien Bastide
University of Chicago
June 5, Day 1, 16:00 - 18:00
The non-specific lethal (NSL) complex prevents R-loop dependent DNA replication stress
Jolanthe Lingeman
Leiden University Medical Center
June 5, Day 1, 16:00 - 18:00
Track & trace transcription factors through truncations
Wim de Jonge
Netherlands Cancer Institute
June 5, Day 1, 16:00 - 18:00
Transcriptional units form the elementary constraining building blocks of the bacterial chromosome
Amaury Bignaud
Institut Pasteur - Régulation Spatiale des Génomes
June 5, Day 1, 16:00 - 18:00